The Sarah Van Hoosen Jones papers document her academic, agricultural, and civic accomplishments, and her interest in local Rochester history, but offer a very incomplete record of her activities as a farmer and a member of the State Board of Agriculture, and the Association of Governing Boards of State Universities and Allied Institutions. In her master's thesis and scientific articles, she discusses theories of dairy farm management and animal genetics, but there is almost no information regarding their later application on her farm. Her files relating to her public service add little to the official record, and her letters consist primarily of invitations, messages of congratulation, and letters of appreciation.

The family papers include a genealogy, letters sent to family members, and tax receipts for the farm. Letters to Joshua Van Hoosen, Sarah's grandfather, were written by Rochester friends and neighbors while he was in California from 1852 to 1853; two other letters, dated 1889 and 1892, are from Wilfred A. Brotherton, a Michigan botanist. Letters to Joseph C. Jones and his wife concern the former's career as a school administrator and editor and include letters from American author William Dean Howells. The Bertha Van Hoosen materials evidence her interest in the role of women in the medical profession.

The collection also includes material relating to Van Hoosen Jones’ cattle herd. Materials include breeding records, sale logs, records relating to the Holstein-Friesen herd, and record books relating to specific farms. Also included are certificates of registry for cows, bulls, Guernseys, and Holsteins. The certificates for the cows and bulls are arranged alphabetically by name followed by the certificates for Guernseys and Holsteins. Also of note is folder of materials relating to a committee that Van Hoosen was on to fight Bang's Disease.

The collection also contains photographs and postcards.

The three rolls of microfilm are positive copies of materials held at the Rochester Hills museum and are on permanent loan to the MSUAHC.