The Ruth Simms Hamilton papers consist of subject files and research materials on African American issues, including civil rights and affirmative action at MSU and other universities. The collection includes case studies of MSU conflicts and protests, newspaper clippings, files about other countries, files about university programs, and papers written by Hamilton and others.

Also included are files about MSU student organizations which include Akers Black Caucus, Associated Black Students of Sociology, Black Brothers of Emmons, Black Brothers of Shaw, Black Liberation Front, Black Caucus, Black Med Students, Black Pre-Med (WAGANGA), Black Sisters of Rather, Black Student Alliance, Black Students of Engineering, Black United Front, Coalition of Black Athletes, Minority Pre Law, Pan African Students Organization of the Americas, United Blacks of Wonders Hall, and Office of Black Affairs. The collection retains the original subject divisions assigned by Hamilton.