The Lisetta Neukom Higgins collection consists primarily of newsclippings, a scrapbook of newsclippings, and a few complete editions of newspapers - all of which contain the published work of Higgins and span the dates 1907-1917. The newspapers are in frail condition. The scrapbook is in stable, leaning towards frail, condition. In all cases, Higgins faithfully either encircled or marked in some way the articles that she wrote. They have been marked, and often dated, with a black grease pencil.

It is not certain for how many papers Higgins wrote during her career as a reporter. Those most heavily represented here are the Battle Creek Daily Journal, Philadelphia Evening Ledger, Detroit Free Press and Detroit News. In all papers she wrote mainly feature style articles, with heavy emphasis on church (she worked as church editor) and society events. While reporting for Battle Creek, Lisetta covered extensively the activities of J. H. Kellogg and the Battle Creek Sanitarium. This included everything from weekly lecturers to interviews with those seeking treatment, such as Jacob Riis, to the First International Conference for the Betterment of the Race held in 1914.

There are notable gaps in the collection, with only vague reference to her personal life: a December 30, 1912 letter home to her parents while Higgins worked for the Detroit News and Detroit Free Press and a holiday newsletter written by Lisetta to family and friends during the 1966-1967 holiday season.